December 2021
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This is a thread-like structure consisting of a single molecule of DNA, but in the case of archaea and eukaryotes, it also includes histone proteins. The DNA carries the genetic information of the cell. In the bacteria and archaea, the chromosome lies free in the cytoplasm of the cell and consists of a single circle of DNA. In the case of eukaryotes the DNA consists of several separate strands of DNA, each chromosome of which carries different information and all of which are enclosed together in a membrane-bound nucleus inside the cell. The totality of the genetic information in a cell is referred to as the genome.
Comparisons of genomes between various organisms reveal some interesting differences. Humans have 23 pairs of different chromosomes which include more than 3 billion nucleotides (with about 20,000 genes) while the fruit fly has 4 pairs of chromosomes with 175 million nucleotides (about 16,000 genes). By comparison, the bacterium E. coli exhibits about 4.6 million nucleotides all located on single chromosome, Arabidopsis (a type of radish plant) has 5 pairs of chromosomes and 135 million nucleotides, and ferns have 720 or more chromosome pairs with total number of nucleotides as high as 148 billion. There does not seem to be any particular reason for any of these numbers!
The main point of interest however is what happens to the chromosomes in the different kinds of cell. A brief examination of this will reveal a major gulf between the cells with an organized nucleus (eukaryotes) and those which lack such a feature (bacteria and archaea).
The process of cell division (binary fission) is rapid and quite uncomplicated in bacteria and archaea. In bacteria there is one point of replication where the duplication of DNA begins. This point of origin copies itself as the duplication of DNA moves in opposite directions. Once the copying is completed, the duplicated points of origin move apart, each one carrying a circular chromosome with it. In the archaea, the process is similar except that there are a number of points on the chromosome where the duplicating process begins.
For the eukaryotes, the process (mitosis) is much more complicated and much slower. As there are a number of linear chromosomes in the nucleus, care must be taken to make sure all the right chromosomes get into the new identical daughter cells. This multi-step process proceeds as follows:
- The linear chromosomes replicate so that each now consists of 2 chromatids held together by the centromere.
- The nuclear membrane and nucleolus disappear and microtubules organize to form the mitotic spindle.
- A proteinaceous body the kinetochore develops on the centromere and attaches each chromatid to a spindle fibre.
- The spindle draws the set of chromatids apart.
- The spindle and one complete set of chromatids move to one end of the cell with the other set going the opposite direction. The nuclear envelope reforms, and two identical daughter cells are formed by cell division. The chromosomes lose some of their compact structure and become invisible in the nucleus.
There are many special innovations in this process, including: the centromere which is a region of condensed DNA forming the ‘waist-line’ in the chromosome; the kinetochore, a histone-type of protein body; the appearance of spindle microtubules; the attachment of kinetochore to microtubule; the disappearance and later reforming of the complicated nuclear envelope (which is also unique to eukaryotes); the coordinated pulling of the chromosomes by the spindle fibres; and the subsequent process of cell division.
But those are not all the innovations in the eukaryotic cell!
Some single celled eukaryotes exhibit only mitotic cell division (and asexual reproduction) but most multicellular eukaryotes exhibit meiosis as well (and sexual reproduction). Meiosis is necessary for sexual reproduction. Sexual reproduction occurs in an individual whose cells are diploid. A diploid cell has 2 complete sets of chromosomes. One set comes from the mother and the other set comes from the father. However, to keep the number of chromosomes from escalating in every following generation, there must be a process to reduce the number of chromosomes in the sex cells (eggs and sperm) down to one set again (haploid) before a new fertilization event. This process of going down to one set of chromosomes is called meiosis. It is much more complicated than mitosis!
There are four novel steps in meiosis which are not present in mitosis:
- Pairing of homologous (containing information on the same traits) chromosomes. One of the pair comes from the mother, the other from the father.
- These paired chromosomes make contact with each other at various points as they lie parallel and breaks occur at these break points and pieces of DNA (between two breaks) are exchanged. These exchanges are called cross-overs and result in new chromosomes that are not the same as those received from each parent.
- During the first meiotic division, homologous chromosomes separate to opposite ends of the cell with the result that two new cells are formed. There are now only half the chromosomes in each daughter cell.
- During the second meiotic division, sister chromatids move to opposite ends. Two new daughter cells are formed from each of the daughters from the first division. These new cells are oriented at right angles to the original daughter pair. Unlike with mitosis, there is no replication of genetic material involved in this cell division.
- The end result is four haploid daughter cells none of which is identical to any of the others.
There is a great deal of information required to coordinate this activity and bring about meiosis! This all has to be programmed into the DNA.
Scientists really have no plausible ideas for how meiosis could have developed through evolutionary processes. However, meiosis is only one problem with the origin of the eukaryotic cell. Mitosis is also a huge problem. There are several competing theories as to how all these features of the eukaryotic cell could have appeared through spontaneous unguided processes. It goes without saying that many scientists believe that the common ancestor of all eukaryotes arose from some kind of cell without a nucleus, but whether it was bacterial or archaeal is much debated, and exactly how this might happen remains unknown.
The special capabilities of the eukaryotic cell actually cry out that they were designed. The complexity and finesse of these features simply could not develop from the unpromising material of bacteria and archaea.
Related Resources
Order OnlinePaperback / $6.00 / 55 Pages
This is a thread-like structure consisting of a single molecule of DNA, but in the case of archaea and eukaryotes, it also includes histone proteins. The DNA carries the genetic information of the cell. In the bacteria and archaea, the chromosome lies free in the cytoplasm of the cell and consists of a single circle of DNA. In the case of eukaryotes the DNA consists of several separate strands of DNA, each chromosome of which carries different information and all of which are enclosed together in a membrane-bound nucleus inside the cell. The totality of the genetic information in a cell is referred to as the genome.
Comparisons of genomes between various organisms reveal some interesting differences. Humans have 23 pairs of different chromosomes which include more than 3 billion nucleotides (with about 20,000 genes) while the fruit fly has 4 pairs of chromosomes with 175 million nucleotides (about 16,000 genes). By comparison, the bacterium E. coli exhibits about 4.6 million nucleotides all located on single chromosome, Arabidopsis (a type of radish plant) has 5 pairs of chromosomes and 135 million nucleotides, and ferns have 720 or more chromosome pairs with total number of nucleotides as high as 148 billion. There does not seem to be any particular reason for any of these numbers!
The main point of interest however is what happens to the chromosomes in the different kinds of cell. A brief examination of this will reveal a major gulf between the cells with an organized nucleus (eukaryotes) and those which lack such a feature (bacteria and archaea).
The process of cell division (binary fission) is rapid and quite uncomplicated in bacteria and archaea. In bacteria there is one point of replication where the duplication of DNA begins. This point of origin copies itself as the duplication of DNA moves in opposite directions. Once the copying is completed, the duplicated points of origin move apart, each one carrying a circular chromosome with it. In the archaea, the process is similar except that there are a number of points on the chromosome where the duplicating process begins.
For the eukaryotes, the process (mitosis) is much more complicated and much slower. As there are a number of linear chromosomes in the nucleus, care must be taken to make sure all the right chromosomes get into the new identical daughter cells. This multi-step process proceeds as follows:
- The linear chromosomes replicate so that each now consists of 2 chromatids held together by the centromere.
- The nuclear membrane and nucleolus disappear and microtubules organize to form the mitotic spindle.
- A proteinaceous body the kinetochore develops on the centromere and attaches each chromatid to a spindle fibre.
- The spindle draws the set of chromatids apart.
- The spindle and one complete set of chromatids move to one end of the cell with the other set going the opposite direction. The nuclear envelope reforms, and two identical daughter cells are formed by cell division. The chromosomes lose some of their compact structure and become invisible in the nucleus.
There are many special innovations in this process, including: the centromere which is a region of condensed DNA forming the ‘waist-line’ in the chromosome; the kinetochore, a histone-type of protein body; the appearance of spindle microtubules; the attachment of kinetochore to microtubule; the disappearance and later reforming of the complicated nuclear envelope (which is also unique to eukaryotes); the coordinated pulling of the chromosomes by the spindle fibres; and the subsequent process of cell division.
But those are not all the innovations in the eukaryotic cell!
Some single celled eukaryotes exhibit only mitotic cell division (and asexual reproduction) but most multicellular eukaryotes exhibit meiosis as well (and sexual reproduction). Meiosis is necessary for sexual reproduction. Sexual reproduction occurs in an individual whose cells are diploid. A diploid cell has 2 complete sets of chromosomes. One set comes from the mother and the other set comes from the father. However, to keep the number of chromosomes from escalating in every following generation, there must be a process to reduce the number of chromosomes in the sex cells (eggs and sperm) down to one set again (haploid) before a new fertilization event. This process of going down to one set of chromosomes is called meiosis. It is much more complicated than mitosis!
There are four novel steps in meiosis which are not present in mitosis:
- Pairing of homologous (containing information on the same traits) chromosomes. One of the pair comes from the mother, the other from the father.
- These paired chromosomes make contact with each other at various points as they lie parallel and breaks occur at these break points and pieces of DNA (between two breaks) are exchanged. These exchanges are called cross-overs and result in new chromosomes that are not the same as those received from each parent.
- During the first meiotic division, homologous chromosomes separate to opposite ends of the cell with the result that two new cells are formed. There are now only half the chromosomes in each daughter cell.
- During the second meiotic division, sister chromatids move to opposite ends. Two new daughter cells are formed from each of the daughters from the first division. These new cells are oriented at right angles to the original daughter pair. Unlike with mitosis, there is no replication of genetic material involved in this cell division.
- The end result is four haploid daughter cells none of which is identical to any of the others.
There is a great deal of information required to coordinate this activity and bring about meiosis! This all has to be programmed into the DNA.
Scientists really have no plausible ideas for how meiosis could have developed through evolutionary processes. However, meiosis is only one problem with the origin of the eukaryotic cell. Mitosis is also a huge problem. There are several competing theories as to how all these features of the eukaryotic cell could have appeared through spontaneous unguided processes. It goes without saying that many scientists believe that the common ancestor of all eukaryotes arose from some kind of cell without a nucleus, but whether it was bacterial or archaeal is much debated, and exactly how this might happen remains unknown.
The special capabilities of the eukaryotic cell actually cry out that they were designed. The complexity and finesse of these features simply could not develop from the unpromising material of bacteria and archaea.
Related Resources
Order OnlineHardcover / $52.00 / 433 Pages
This is a thread-like structure consisting of a single molecule of DNA, but in the case of archaea and eukaryotes, it also includes histone proteins. The DNA carries the genetic information of the cell. In the bacteria and archaea, the chromosome lies free in the cytoplasm of the cell and consists of a single circle of DNA. In the case of eukaryotes the DNA consists of several separate strands of DNA, each chromosome of which carries different information and all of which are enclosed together in a membrane-bound nucleus inside the cell. The totality of the genetic information in a cell is referred to as the genome.
Comparisons of genomes between various organisms reveal some interesting differences. Humans have 23 pairs of different chromosomes which include more than 3 billion nucleotides (with about 20,000 genes) while the fruit fly has 4 pairs of chromosomes with 175 million nucleotides (about 16,000 genes). By comparison, the bacterium E. coli exhibits about 4.6 million nucleotides all located on single chromosome, Arabidopsis (a type of radish plant) has 5 pairs of chromosomes and 135 million nucleotides, and ferns have 720 or more chromosome pairs with total number of nucleotides as high as 148 billion. There does not seem to be any particular reason for any of these numbers!
The main point of interest however is what happens to the chromosomes in the different kinds of cell. A brief examination of this will reveal a major gulf between the cells with an organized nucleus (eukaryotes) and those which lack such a feature (bacteria and archaea).
The process of cell division (binary fission) is rapid and quite uncomplicated in bacteria and archaea. In bacteria there is one point of replication where the duplication of DNA begins. This point of origin copies itself as the duplication of DNA moves in opposite directions. Once the copying is completed, the duplicated points of origin move apart, each one carrying a circular chromosome with it. In the archaea, the process is similar except that there are a number of points on the chromosome where the duplicating process begins.
For the eukaryotes, the process (mitosis) is much more complicated and much slower. As there are a number of linear chromosomes in the nucleus, care must be taken to make sure all the right chromosomes get into the new identical daughter cells. This multi-step process proceeds as follows:
- The linear chromosomes replicate so that each now consists of 2 chromatids held together by the centromere.
- The nuclear membrane and nucleolus disappear and microtubules organize to form the mitotic spindle.
- A proteinaceous body the kinetochore develops on the centromere and attaches each chromatid to a spindle fibre.
- The spindle draws the set of chromatids apart.
- The spindle and one complete set of chromatids move to one end of the cell with the other set going the opposite direction. The nuclear envelope reforms, and two identical daughter cells are formed by cell division. The chromosomes lose some of their compact structure and become invisible in the nucleus.
There are many special innovations in this process, including: the centromere which is a region of condensed DNA forming the ‘waist-line’ in the chromosome; the kinetochore, a histone-type of protein body; the appearance of spindle microtubules; the attachment of kinetochore to microtubule; the disappearance and later reforming of the complicated nuclear envelope (which is also unique to eukaryotes); the coordinated pulling of the chromosomes by the spindle fibres; and the subsequent process of cell division.
But those are not all the innovations in the eukaryotic cell!
Some single celled eukaryotes exhibit only mitotic cell division (and asexual reproduction) but most multicellular eukaryotes exhibit meiosis as well (and sexual reproduction). Meiosis is necessary for sexual reproduction. Sexual reproduction occurs in an individual whose cells are diploid. A diploid cell has 2 complete sets of chromosomes. One set comes from the mother and the other set comes from the father. However, to keep the number of chromosomes from escalating in every following generation, there must be a process to reduce the number of chromosomes in the sex cells (eggs and sperm) down to one set again (haploid) before a new fertilization event. This process of going down to one set of chromosomes is called meiosis. It is much more complicated than mitosis!
There are four novel steps in meiosis which are not present in mitosis:
- Pairing of homologous (containing information on the same traits) chromosomes. One of the pair comes from the mother, the other from the father.
- These paired chromosomes make contact with each other at various points as they lie parallel and breaks occur at these break points and pieces of DNA (between two breaks) are exchanged. These exchanges are called cross-overs and result in new chromosomes that are not the same as those received from each parent.
- During the first meiotic division, homologous chromosomes separate to opposite ends of the cell with the result that two new cells are formed. There are now only half the chromosomes in each daughter cell.
- During the second meiotic division, sister chromatids move to opposite ends. Two new daughter cells are formed from each of the daughters from the first division. These new cells are oriented at right angles to the original daughter pair. Unlike with mitosis, there is no replication of genetic material involved in this cell division.
- The end result is four haploid daughter cells none of which is identical to any of the others.
There is a great deal of information required to coordinate this activity and bring about meiosis! This all has to be programmed into the DNA.
Scientists really have no plausible ideas for how meiosis could have developed through evolutionary processes. However, meiosis is only one problem with the origin of the eukaryotic cell. Mitosis is also a huge problem. There are several competing theories as to how all these features of the eukaryotic cell could have appeared through spontaneous unguided processes. It goes without saying that many scientists believe that the common ancestor of all eukaryotes arose from some kind of cell without a nucleus, but whether it was bacterial or archaeal is much debated, and exactly how this might happen remains unknown.
The special capabilities of the eukaryotic cell actually cry out that they were designed. The complexity and finesse of these features simply could not develop from the unpromising material of bacteria and archaea.
Related Resources
Order OnlinePaperback / $28.00 / 256 Pages
This is a thread-like structure consisting of a single molecule of DNA, but in the case of archaea and eukaryotes, it also includes histone proteins. The DNA carries the genetic information of the cell. In the bacteria and archaea, the chromosome lies free in the cytoplasm of the cell and consists of a single circle of DNA. In the case of eukaryotes the DNA consists of several separate strands of DNA, each chromosome of which carries different information and all of which are enclosed together in a membrane-bound nucleus inside the cell. The totality of the genetic information in a cell is referred to as the genome.
Comparisons of genomes between various organisms reveal some interesting differences. Humans have 23 pairs of different chromosomes which include more than 3 billion nucleotides (with about 20,000 genes) while the fruit fly has 4 pairs of chromosomes with 175 million nucleotides (about 16,000 genes). By comparison, the bacterium E. coli exhibits about 4.6 million nucleotides all located on single chromosome, Arabidopsis (a type of radish plant) has 5 pairs of chromosomes and 135 million nucleotides, and ferns have 720 or more chromosome pairs with total number of nucleotides as high as 148 billion. There does not seem to be any particular reason for any of these numbers!
The main point of interest however is what happens to the chromosomes in the different kinds of cell. A brief examination of this will reveal a major gulf between the cells with an organized nucleus (eukaryotes) and those which lack such a feature (bacteria and archaea).
The process of cell division (binary fission) is rapid and quite uncomplicated in bacteria and archaea. In bacteria there is one point of replication where the duplication of DNA begins. This point of origin copies itself as the duplication of DNA moves in opposite directions. Once the copying is completed, the duplicated points of origin move apart, each one carrying a circular chromosome with it. In the archaea, the process is similar except that there are a number of points on the chromosome where the duplicating process begins.
For the eukaryotes, the process (mitosis) is much more complicated and much slower. As there are a number of linear chromosomes in the nucleus, care must be taken to make sure all the right chromosomes get into the new identical daughter cells. This multi-step process proceeds as follows:
- The linear chromosomes replicate so that each now consists of 2 chromatids held together by the centromere.
- The nuclear membrane and nucleolus disappear and microtubules organize to form the mitotic spindle.
- A proteinaceous body the kinetochore develops on the centromere and attaches each chromatid to a spindle fibre.
- The spindle draws the set of chromatids apart.
- The spindle and one complete set of chromatids move to one end of the cell with the other set going the opposite direction. The nuclear envelope reforms, and two identical daughter cells are formed by cell division. The chromosomes lose some of their compact structure and become invisible in the nucleus.
There are many special innovations in this process, including: the centromere which is a region of condensed DNA forming the ‘waist-line’ in the chromosome; the kinetochore, a histone-type of protein body; the appearance of spindle microtubules; the attachment of kinetochore to microtubule; the disappearance and later reforming of the complicated nuclear envelope (which is also unique to eukaryotes); the coordinated pulling of the chromosomes by the spindle fibres; and the subsequent process of cell division.
But those are not all the innovations in the eukaryotic cell!
Some single celled eukaryotes exhibit only mitotic cell division (and asexual reproduction) but most multicellular eukaryotes exhibit meiosis as well (and sexual reproduction). Meiosis is necessary for sexual reproduction. Sexual reproduction occurs in an individual whose cells are diploid. A diploid cell has 2 complete sets of chromosomes. One set comes from the mother and the other set comes from the father. However, to keep the number of chromosomes from escalating in every following generation, there must be a process to reduce the number of chromosomes in the sex cells (eggs and sperm) down to one set again (haploid) before a new fertilization event. This process of going down to one set of chromosomes is called meiosis. It is much more complicated than mitosis!
There are four novel steps in meiosis which are not present in mitosis:
- Pairing of homologous (containing information on the same traits) chromosomes. One of the pair comes from the mother, the other from the father.
- These paired chromosomes make contact with each other at various points as they lie parallel and breaks occur at these break points and pieces of DNA (between two breaks) are exchanged. These exchanges are called cross-overs and result in new chromosomes that are not the same as those received from each parent.
- During the first meiotic division, homologous chromosomes separate to opposite ends of the cell with the result that two new cells are formed. There are now only half the chromosomes in each daughter cell.
- During the second meiotic division, sister chromatids move to opposite ends. Two new daughter cells are formed from each of the daughters from the first division. These new cells are oriented at right angles to the original daughter pair. Unlike with mitosis, there is no replication of genetic material involved in this cell division.
- The end result is four haploid daughter cells none of which is identical to any of the others.
There is a great deal of information required to coordinate this activity and bring about meiosis! This all has to be programmed into the DNA.
Scientists really have no plausible ideas for how meiosis could have developed through evolutionary processes. However, meiosis is only one problem with the origin of the eukaryotic cell. Mitosis is also a huge problem. There are several competing theories as to how all these features of the eukaryotic cell could have appeared through spontaneous unguided processes. It goes without saying that many scientists believe that the common ancestor of all eukaryotes arose from some kind of cell without a nucleus, but whether it was bacterial or archaeal is much debated, and exactly how this might happen remains unknown.
The special capabilities of the eukaryotic cell actually cry out that they were designed. The complexity and finesse of these features simply could not develop from the unpromising material of bacteria and archaea.
Related Resources
Order OnlinePaperback / $16.00 / 189 Pages / line drawings
This is a thread-like structure consisting of a single molecule of DNA, but in the case of archaea and eukaryotes, it also includes histone proteins. The DNA carries the genetic information of the cell. In the bacteria and archaea, the chromosome lies free in the cytoplasm of the cell and consists of a single circle of DNA. In the case of eukaryotes the DNA consists of several separate strands of DNA, each chromosome of which carries different information and all of which are enclosed together in a membrane-bound nucleus inside the cell. The totality of the genetic information in a cell is referred to as the genome.
Comparisons of genomes between various organisms reveal some interesting differences. Humans have 23 pairs of different chromosomes which include more than 3 billion nucleotides (with about 20,000 genes) while the fruit fly has 4 pairs of chromosomes with 175 million nucleotides (about 16,000 genes). By comparison, the bacterium E. coli exhibits about 4.6 million nucleotides all located on single chromosome, Arabidopsis (a type of radish plant) has 5 pairs of chromosomes and 135 million nucleotides, and ferns have 720 or more chromosome pairs with total number of nucleotides as high as 148 billion. There does not seem to be any particular reason for any of these numbers!
The main point of interest however is what happens to the chromosomes in the different kinds of cell. A brief examination of this will reveal a major gulf between the cells with an organized nucleus (eukaryotes) and those which lack such a feature (bacteria and archaea).
The process of cell division (binary fission) is rapid and quite uncomplicated in bacteria and archaea. In bacteria there is one point of replication where the duplication of DNA begins. This point of origin copies itself as the duplication of DNA moves in opposite directions. Once the copying is completed, the duplicated points of origin move apart, each one carrying a circular chromosome with it. In the archaea, the process is similar except that there are a number of points on the chromosome where the duplicating process begins.
For the eukaryotes, the process (mitosis) is much more complicated and much slower. As there are a number of linear chromosomes in the nucleus, care must be taken to make sure all the right chromosomes get into the new identical daughter cells. This multi-step process proceeds as follows:
- The linear chromosomes replicate so that each now consists of 2 chromatids held together by the centromere.
- The nuclear membrane and nucleolus disappear and microtubules organize to form the mitotic spindle.
- A proteinaceous body the kinetochore develops on the centromere and attaches each chromatid to a spindle fibre.
- The spindle draws the set of chromatids apart.
- The spindle and one complete set of chromatids move to one end of the cell with the other set going the opposite direction. The nuclear envelope reforms, and two identical daughter cells are formed by cell division. The chromosomes lose some of their compact structure and become invisible in the nucleus.
There are many special innovations in this process, including: the centromere which is a region of condensed DNA forming the ‘waist-line’ in the chromosome; the kinetochore, a histone-type of protein body; the appearance of spindle microtubules; the attachment of kinetochore to microtubule; the disappearance and later reforming of the complicated nuclear envelope (which is also unique to eukaryotes); the coordinated pulling of the chromosomes by the spindle fibres; and the subsequent process of cell division.
But those are not all the innovations in the eukaryotic cell!
Some single celled eukaryotes exhibit only mitotic cell division (and asexual reproduction) but most multicellular eukaryotes exhibit meiosis as well (and sexual reproduction). Meiosis is necessary for sexual reproduction. Sexual reproduction occurs in an individual whose cells are diploid. A diploid cell has 2 complete sets of chromosomes. One set comes from the mother and the other set comes from the father. However, to keep the number of chromosomes from escalating in every following generation, there must be a process to reduce the number of chromosomes in the sex cells (eggs and sperm) down to one set again (haploid) before a new fertilization event. This process of going down to one set of chromosomes is called meiosis. It is much more complicated than mitosis!
There are four novel steps in meiosis which are not present in mitosis:
- Pairing of homologous (containing information on the same traits) chromosomes. One of the pair comes from the mother, the other from the father.
- These paired chromosomes make contact with each other at various points as they lie parallel and breaks occur at these break points and pieces of DNA (between two breaks) are exchanged. These exchanges are called cross-overs and result in new chromosomes that are not the same as those received from each parent.
- During the first meiotic division, homologous chromosomes separate to opposite ends of the cell with the result that two new cells are formed. There are now only half the chromosomes in each daughter cell.
- During the second meiotic division, sister chromatids move to opposite ends. Two new daughter cells are formed from each of the daughters from the first division. These new cells are oriented at right angles to the original daughter pair. Unlike with mitosis, there is no replication of genetic material involved in this cell division.
- The end result is four haploid daughter cells none of which is identical to any of the others.
There is a great deal of information required to coordinate this activity and bring about meiosis! This all has to be programmed into the DNA.
Scientists really have no plausible ideas for how meiosis could have developed through evolutionary processes. However, meiosis is only one problem with the origin of the eukaryotic cell. Mitosis is also a huge problem. There are several competing theories as to how all these features of the eukaryotic cell could have appeared through spontaneous unguided processes. It goes without saying that many scientists believe that the common ancestor of all eukaryotes arose from some kind of cell without a nucleus, but whether it was bacterial or archaeal is much debated, and exactly how this might happen remains unknown.
The special capabilities of the eukaryotic cell actually cry out that they were designed. The complexity and finesse of these features simply could not develop from the unpromising material of bacteria and archaea.